CALL FOR PAPERS Pathophysiology of Hypertension Respiratory influences on muscle sympathetic nerve activity and vascular conductance in the steady state

نویسندگان

  • Jacqueline K. Limberg
  • Barbara J. Morgan
  • William G. Schrage
  • Jerome A. Dempsey
چکیده

Jacqueline K. Limberg, Barbara J. Morgan, William G. Schrage, and Jerome A. Dempsey John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Madison, Wisconsin; Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin; Department of Orthopedics and Rehabilitation, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin; and Bruno Balke Biodynamics Laboratory, Department of Kinesiology, School of Education, University of Wisconsin, Madison, Wisconsin

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Respiratory influences on muscle sympathetic nerve activity and vascular conductance in the steady state.

In patients with hypertension, volitional slowing of the respiratory rate has been purported to reduce arterial pressure via withdrawal of sympathetic tone. We examined the effects of paced breathing at 7, 14, and 21 breaths/min, with reciprocal changes in tidal volume, on muscle sympathetic nerve activity, forearm blood flow, forearm vascular conductance, and blood pressure in 21 men and women...

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Tonic and reflex control of the cardio-respiratory system by neurons in the ventral medulla

To investigate the channels and neurotransmitters in the ventrolateral medulla (VLM) oblongata that are responsible for the maintenance of sympathetic tone and cardio-respiratory reflex regulation. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM), calcium channel blockers, agonists and antagonists were made throughout the VLM in anaesthetized rats. Arterial blood pressure, sym...

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Nerve growth factor synthesis in vascular smooth muscle.

Details of the interdependent, trophic relation between smooth muscle and its neural innervation are not well known despite suggestions that neural influences may contribute significantly to hypertensive and other cardiovascular disease. Vascular smooth muscle is a major target of innervation by neurons of the sympathetic nervous system. Sympathetic neurons depend on a constant supply of the po...

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Alpha males: muscle sympathetic discharge on beat-to-beat forearm vascular conductance.

The sympathetic nervous system is an important regulator of arterial pressure due to its dynamic effects on vascular tone and cardiac output. With respect to the former, postganglionic sympathetic neurons innervate the adventitial–medial borders of most blood vessels and when stimulated release noradrenaline (norepinephrine; along with other co-transmitters) which bind to postsynaptic α-adrener...

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تاریخ انتشار 2013